Current Research Projects

-> You can find the complete Status Report 2016-2017 as a PDF file here.

Work Groups and Work Group Leaders (Last Update: 08/05/2018)

Leitung: Prof. Dr. Katja Beesdo-Baum, Dr. Lars Pieper, Prof. Dr. J. Rehm & Prof. Dr. Hans-Ulrich Wittchen
P1. The Epidemiological Functional and Dysfunctional Behavioral and Psychological Factors in Mental Health and Disease (EBP)
P2. Early Developmental Stages of Psychopathology (EDSP): Natural course, etiology, and pathogenesis of mental and substance use disorders
P3. The German Health Interview and Examination Survey for Adults Mental Health Supplement (DEGS1-MH)
P4. Bundesweite Studie zum Versorgungsverlauf bei Depression in Arztpraxen/National survey on health care of depression in German primary care practices (VERA)
P5. Mental Disorders in the elderly: Relationship to impairment, functioning (ICF) and service utilisation (MentDis_ICF65+)
P6. Suicidal behaviour across the life span – risk and protective factors
P7. Examining the role of genetic vulnerabilities and environmental stressors for anxiety disorders: Evidence for individual, combined and interactive effects as well as disorder-specificity?
P8. Lifetime prevalence of mental disorders among first and second generation individuals with Turkish migration backgrounds in Germany
P9. Acculturation and other risk factors of depressive disorders in individuals with Turkish migration backgrounds
AG 2 Experimental Clinical Psychology and Neuroimaging
Leitung: PD Dr. Ulrike Lüken, Prof. Dr. Katja Beesdo-Baum & Dr. Markus Mühlhan
P1. Epigenetic variation in the serotonin transporter gene predicts resting state functional connectivity strength within the salience-network
P2. Stress-related salivary alpha-amylase (sAA) activity in alcohol dependent patients with and without a history of childhood maltreatment
P3. Neurostructural correlates and cortisol responses in Generalized Anxiety Disorder versus other anxiety conditions and depression: Evidence for specificity
P4. Differentielle neuro-biologische Korrelate der Emotions- und Stressverarbeitung bei Generalisierter Angststörung im Vergleich zu Major Depression und
Sozialer Phobie / Differential neuro-biological correlates of emotion - and stress-processing in generalized anxiety disorder vs. major depression

P5. Avoidance behavior as a result of one-sided exertion of cognitive control in specific phobia. A subproject within the collaborative research center (CRC 940) on “Volition and Cognitive Control” (Speaker: Goschke, T.)
P6. Neural correlates and predictors of mental health and disease in adolescents and young adults from the community
P7. Psychophysiological and neural reactivity during uncertainty and ambiguity processing in high and low worriers
P8. Behavioral avoidance and cognitive control abilities in high and low worriers
P9. ENIGMA – Subcortical volumes in social anxiety disorder
P10. Separating depressive comorbidity from panic disorder: A combined functional magnetic resonance imaging and machine learning approach
P11. Neural correlates of individual differences in anxiety sensitivity: An fMRI study using semantic priming
P12. Probing the interoceptive network by listening to heartbeats: An fMRI study
P13. Support vector machine analysis of functional magnetic resonance imaging of interoception does not reliably predict individual outcomes of cognitive behavioral therapy in panic disorder with agoraphobia
AG 3 Women’s and Infant’s Health
Leitung: Dr. Julia Martini & Prof. Dr. Hans-Ulrich Wittchen
P1. Maternal anxiety and depression in relation to infant development (MARI Study)
P2. Natural course of mental disorders in women during reproductive phases
P3. Mental and physical health in parents of chronically ill children<
Leitung: Prof. Dr. Hans-Ulrich Wittchen & Dr. Susanne Knappe
Leitung: S. Trautmann, J. Schäfer & H.-U. Wittchen
P1. Evidence for two different ICD-11 posttraumatic stress disorders in a community sample of adolescents and young adults
P2. Trauma-related mental disorders in the general population
P3. Mental health consequences of military deployment
P4. Underlying mechanisms in the association between stressful experiences and alcohol use
P5. Consequences of (early) traumatization for the treatment of mental disorders in adulthood
P6. Attentional Bias in Posttraumatic Stress Disorder: A Temporal Dynamics Process Perspective
P7. Stressful experiences, attentional control and suicidality
Leitung: G. Bühringer, SINCE 2016: T. Endrass, A. Kräplin, S. Behrend & J. Rehm
P1. Work area 2/Work package 5-Counting addiction
P2. Work area 3/Work packages 7-9-Determinants of addiction
P3. Work area 4/Work package 10-Revenues, profits and participants (sub-study on prison interviews)
P4. Work area 5/Work package 13.1-Theoretical overview of governance views
P5. Work area 3/Work packages 7-9-Transition probabilities between different stages of substance use
P6. Doctoral thesis: Individuumsbezogene Prädiktoren für Entwicklung und Verlauf problematischen Cannabiskonsums in der Allgemeinbevölkerung und bei Patienten in Psychotherapie
P7. „Addiction: Early recognition and intervention across the lifespan (AERIAL)”; Teilprojekt P8, Technische Universität Dresden
P8. The temporal relationship between internet gaming disorder symptoms and dysfunctional decision-making Staff: Dr. A. Kräplin; re-analysis of data from the project „Verlauf und Stabilität von problematischem Computerspielverhalten über einen Zeitraum von drei Jahren“
P9: Addiction as disorder of volition: Impaired cognitive control functions in nicotine dependence and pathological gambling
P10. Volitional dysfunction in self-control failures and addictive behaviors
P11. Pilot project: The role of cognitive dysfunctions in predicting real-life gambling behaviour (GAP)
P12. The effect of negative interpersonal scenes on inhibitory control and decision-making in gambling disorder Staff: Dr. A. Kräplin; re-analysis of data from the project “Selbststeuerung, kognitive Kontrolle und Persönlichkeitsaspekte bei der Störung durch Glücksspielen” [Self-control, cognitive control and personality in gambling disorder]
P13. DFG-Research Group FOR 1617 “Learning & habitization as predictors of the development & maintenance of alcoholism”
P14. Project Elderly: Motivational Enhancement Therapy and Community Reinforcement Approach For Treating Alcohol Problems in the Elderly-an international multicenter study
P15. ELDERLY Transfer-Studie
P16. Evaluation of a treatment and control system for pilots with mental disorders
P17. CEGG-Characteristics and follow-up of gamblers from the German casino exclusion program
P18. Doctoral thesis: Psychological and behavioral characteristics of gamblers in a follow-up study from the German Casino Exclusion Program
P19. Development and evaluation of consumer protection in the field of gambling regulation
P20. The vulnerable gambler: characteristics, disorder development, remission, early recognition, and protective measures
Leitung: Prof. Dr. Hans-Ulrich Witttchen & Dr. Lars Pieper
Leitung: Prof. Dr. Corinna Jacobi
P1. Entwicklung eines Online-Screenings zur Erkennung von Essstörungen
P2. everyBody - maßgeschneiderte Online-Prävention von Essstörungen und ernährungsbedingten Erkrankungen in der Allgemeinbevölkerung. Einer Pilotstudie in der Allgemeinbevölkerung.
P3. everyBody – Maßgeschneiderte Online-Gesundheitsförderung und -Essstörungsprävention für Frauen
P4. Internet-gestützte Selbsthilfe zur Überbrückung der Wartezeit auf ambulante Psychotherapie bei Patienten mit Bulimia nervosa, Binge Eating Disorder und OSFED
P5. WE CAN – Angehörige von Menschen mit Magersucht entlasten
P6. Moderators and mediators of adherence and outcomes in ICare
P7. Internet-gestützte Prävention und Frühintervention für junge Frauen mit erhöhtem Risiko der Entwicklung einer Anorexia nervosa
P8. The integrated neurobiology of food intake, addiction and stress (NeuroFAST), Arbeitspaket: “Interrelations between eating disorders and substance use disorders”
Leitung: Prof. Dr. Jürgen Hoyer & Prof. Dr. Katja Beesdo-Baum
P1. PANIC-NET and PROTECT-AD For this project description see section AG 10
P2. Manualized cognitive therapy versus cognitive-behavioral treatment-as-usual for social anxiety disorder in routine practice: A cluster-randomized controlled trial
P3. Daily fluctuation of emotions and memories there of: Design and methods of an event sampling study of major depression, social phobia and controls
P4. Are neurodevelopmental markers and childhood sexual abuse indicative of pedohebephilia? Evidence from an anonymous online survey
P5. Depersonalization and academic stress
P6. Depersonalization, self-control, and cognitive performance
P7. Do “supershrinks” assess therapeutic progress more conservatively?
P8. Verhaltensaktivierende Methoden in der Depressionsbehandlung
P9. Systematic variation of instructions for written fear exposure protocols
P10. A 10 year follow-up of worry exposure and applied relaxation in the treatment of generalized anxiety disorder
P11. Effektivität kognitiver Verhaltenstherapie bei der Behandlung der Generalisierten Angststörung in einer Hochschulambulanz und Prädiktoren des Therapieergebnisses
Leitung: Prof. Dr. Hans-Ulrich Wittchen, Prof. Dr. Jürgen Hoyer & Dr. Andre Pittig
P1. RCT 1: Optimizing extinction using intensified psychological interventions for adult anxiety disorders
P2. RCT 2: Differential impact of parental participation on intensified exposure-based psychological interventions in anxiety disorders in children
P3. Subproject - Behavioral and psychophysiological markers of extinction learning and outcome
P4. Subproject - Neural response and fear circuitry related to extinction learning and outcome
P5. Subproject - (Epi)genetic effects related to extinction learning and outcome
P6. Transfer of exposure-based interventions into the routine provider system
P7. The German research network for mental disorders
P8. Anxiety disorders
P9. Panic disorder with agoraphobia from a behavioral neuroscience perspective: Applying the research principles formulated by the Research Domain Criteria (RDoC) initiative
P10. Treating treatment-resistant patients with panic disorder and agoraphobia using psychotherapy: A randomized controlled switching trial
P11. Predicting treatment response to cognitive-behavioral therapy in panic disorder with agoraphobia by integrating local neural information
P12. Changes of valued behaviors and functioning during an acceptance and commitment therapy intervention
P13. Effects of interoceptive exposure in cognitive-behavioral therapy of panic disorder with agoraphobia
P14. The effects of cognitive preparation on self-directed exposure and symptom reduction in exposurebased CBT for panic disorder and agoraphobia
P15. Vocally encoded emotional arousal during Cognitive Preparation and its Impact on Therapy Outcome for Panic Disorder with Agoraphobia
P16. Dyadic vocally encoded emotional arousal in CBT for panic disorder with agoraphobia
P17. Facing the fear - Clinical and neural effects of cognitive behavioural and pharmacotherapy in panic dis order with agoraphobia
P18. Neurobiological markers predicting treatment response in anxiety disorders: A systematic review and implications for clinical application
P19. 5HTT is associated with the phenotype psychological flexibility: Results from a randomized clinical trial
P20. Probing the interoceptive network by listening to heartbeats: An fMRI study
P21. Support vector machine analysis of functional magnetic resonance imaging of interoception does not reliably predict individual outcomes of cognitive behavioral therapy in panic disorder with agoraphobia
P22. Modulation of defensive reactivity by GLRB allelic variation: Converging evidence from an intermediate phenotype approach
P23. RGS2 genetic variation: Association analysis with panic disorder and dimensional as well as intermediate phenotypes of anxiety
P24. MAOA gene hypomethylation in panic disorder-reversibility of an epigenetic risk pattern by psychotherapy
P25. Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing
Leitung: Prof. Dr. Beesdo-Baum & PD Dr. Susanne Knappe
P1. Effectiveness and underlying mechanisms of applied relaxation as indicated preventive intervention in subjects at increased risk for mental disorders
P2. Indicated prevention of mental disorders in subjects with initial panic symptomatology: effectiveness and underlying mechanisms of action
P3. A pilot randomized controlled trial of a stress management program with and without assertiveness training
P4. Indicated prevention of anxiety disorders in shy children
P5. Systematic screening for anxiety and other emotional problems in children
Leitung: Prof. Dr. Hans-Ulrich Wittchen, Prof. Dr. Katja Beesdo-Baum, PD Dr. Susanne Knappe & Prof. Dr. Jürgen Hoyer
P1. Standardized, computerized assessment of symptoms, syndromes and diagnoses of mental disorders
P2. Strategies and challenges for improving the diagnostics of anxiety disorders
P3. Structured clinical interviews for sexual dysfunctions in women and men according to DSM-5
P4. Ein Screeningverfahren zur Erfassung der Prämenenstruellen Dysphorischen Störung (PMDS) und des Prämenstruellen Syndroms (PMS)
P5. Concordance of the Depression-Screening-Questionnaire (DSQ) with PHQ-9 and DIA-X/M-CIDI and linkage to a common metric of depression severity
P6. The development of novel behavioral assessment methods
P5. Concordance of the Depression-Screening-Questionnaire (DSQ) with PHQ-9 and DIA-X/M-CIDI and linkage to a common metric of depression severity
P7. Erhebung von Referenzdaten zur Bewegungserkennung und Entwicklung eines ML Algorithmus für die Detektion von Bewegungsmustern aus Beschleunigungssensordaten
P8. Diagnostik und Verhaltensanalyse
P9. The Hospital Anxiety and Depression Scale (HADS) and the 9-item Patient Health Questionnaire (PHQ-9) as screening instruments for depression in patients with cancer
P10. Überprüfung der psychometrischen Eigenschaften und der Augenscheinvalidität der deutschen Übersetzung des Youth Anxiety Measure for DSM-5